In File 2, you will see that there are additional lobbies with their own specific rulesets. Here is a small break down for those that are unaware:
- Free Area
Vanilla gameplay. Can select scenarios, eliminations, or showdowns.
- Nightmare
Nightmare mode is on. Enemies deal double damage. Healing items restore half as much HP, except for George's capsule shooter which heals twice as much. 
- Survival
Friendly Fire is on. Teammates can damage each other.
- Panic
Combination of Nightmare and Survival. Nightmare mode and friendly fire are both on.
- Infinity
Infinite ammo for all guns. Melee weapons never lose durability when attacking walls, doors, or enemies. Throw able projectiles are also infinite.
- Item Hunt
Special items twinkle to reveal their location. Your score will also be multiplied at the end of the game.
- Testing
Currently hosting Half-Horror mode. Nightmare is on, 50% starting infection rate, and Special items twinkle to reveal their location.
- Elimination
Only Elimination games are playable.
- Showdown
Only Showdown games are playable.
- SECRET Area
Currently hosting Horror mode. Nightmare is on, 80% starting infection rate, and Special items twinkle to reveal their location.